The historical increases in computing performance and reductions in power consumption, size, weight and cost of computing devices are ingrained in the fabric of the research community. These improvements have fueled innovation across scientific domains, health, industry, and government. But clock speeds have been relatively flat for over a decade and current transistor scaling will be reaching limits that are both technological and economic over the next decade. While alternative models of computation are being explored, including quantum and neuro-inspired, digital computing will remain the dominant computational technology for the foreseeable future.